The Byrne Lab at the University of Pittsburgh

The Byrne Lab, in the Departments of Ophthalmology, Neurobiology and Bioengineering at the University of Pittsburgh, is recruiting for multiple open positions.

Protein biologist

Together with the Betegon lab (https://betegonlab.science/) we are seeking a research scientist to work on the development of next generation of AAV vector systems with enhanced capabilities. The researcher will assist in the design, development and evaluation of these novel AAV systems, present research findings at meetings, and contribute to the preparation of manuscripts.

The candidate must have a PhD in biology, biophysics, biochemistry, or related field, as well as demonstrated experience in protein expression and purification. Experience in protein engineering or structural biology is desired. Previous experience working with AAV is not required.

To apply please email Dr. Betegon (mib145@pitt.edu) or Dr. Byrne (lbyrne@pitt.edu) with your CV and a cover letter.

Computational biologist

The Byrne Lab is looking for a full-time Bioinformatics Specialist to join the team in developing and advancing retinal gene therapies using next-generation sequencing analysis. Job duties will include creating workflows/pipelines for various projects, managing/storing sequencing data, and assisting in the design of sequencing experiments. The candidate must be comfortable with running jobs on HPC and should be proficient in R. Current projects include analysis of scRNA-seq, scATAC-seq, and custom targeted panel datasets. The candidate must be adaptive to new projects/sequencing experiments and work well in a team environment.